Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16972 Torin-2 GSE70138 MCF10A Human 3h 10uM EID0009
Types Number Response transcription factors
Up-regulation 60 NR3C1; TSC22D3; SOX4; PSPC1; NFKBIA; DDIT3; BRD8; HBP1; UIMC1; ECD; UBE2B; ARID4B; BHLHE40; PPARGC1A; RBPMS; GATA2; ZBTB18; RCOR3; NFX1; ZNF226; TRIM22; PHF20; RNF10; MEF2A; ENO1; MYB; CENPF; ZMIZ2; SAP30; RORA; NRIP1; RFX5; HOXC6; NR1H2; BTG1; AFF1; TBL1XR1; MAFB; CBX3; HOXC10; STAT1; HMGB2; ING3; DMTF1; HMGB1; SMARCA2; ELF1; NFIB; TRIP6; LPIN2; KLF2; MAF; TLE1; ID2; BASP1; ELK3; ATF3; ASCL1; NFIL3; ERBB2
Down-regulation 108 IKBKAP; ATF5; SRF; HMGA2; MYC; TAF9; HES1; JUNB; FOSL1; CBX6; KLF4; HOXA10; HOXD10; INSM1; CARM1; PPRC1; HOXD11; NR4A3; PITX1; VDR; CSDE1; SNAI2; MAFF; KLF10; EGR1; NR0B1; FOXF2; SMARCB1; THAP7; HDAC4; NR0B2; RNF138; HMG20B; NKX3-1; PROX1; MNX1; ADRB2; JUN; ZFP37; TFAP2A; NHLH2; SF1; SOX9; PRDM12; GFI1B; SIX2; ZNF711; EHF; HIC2; MYT1L; FOXA2; CEBPZ; ID1; SIX3; TCEA2; CBFA2T3; ANKRD1; PEG3; NKX2-2; WT1; FOXG1; HIRA; SOHLH2; TOX3; FOSB; AEBP1; PAX6; ZNF512B; ST18; NFE2L3; ETS1; ZBED2; LEF1; SIX6; ZFP36L2; NEUROD1; RUNX3; MYRF; SALL1; ID4; ZIC3; CUX2; DLX5; KLF11; ZNF91; SOX17; NR5A2; SOX11; ESR1; FOXF1; THAP11; TRIB3; SOX2; TCF21; VPS72; HHEX; GATA6; NFATC4; EGR2; EGR3; GLI2; FOS; NR4A2; ARNT2; NFATC3; MEIS2; SATB1; E2F2