Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16968 Pelitinib GSE70138 MCF10A Human 3h 1.11uM EID0009
Types Number Response transcription factors
Up-regulation 18 TSC22D3; XBP1; ID2; DNAJC1; SOX4; DNMT3B; HSBP1; ITGB3BP; RUVBL2; PTTG1; CEBPG; TFDP2; HTATIP2; BRD8; RBBP4; MYCN; HLTF; HOXC6
Down-regulation 50 MYC; HMGA2; EGR1; FOSL1; KLF10; FHL2; ZFP36L1; CEBPD; MED17; ARID4B; PRRX1; HDAC4; EGR3; CREB1; HOXB2; JUNB; NFE2L3; HES1; KAT2B; ADRB2; E2F5; ZEB1; NPAS2; ISL1; BACH2; HIC2; ZBED2; SOX9; EGR2; FOS; HDAC9; IFI16; TBX3; JUN; MYRF; MNDA; ZNF232; MEIS2; IRF8; ZFPM2; HHEX; NR4A2; ELK3; WT1; SOX17; ARNT2; PEG3; SOX11; ERBB4; TBX2