Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16967 Pelitinib GSE70138 MCF10A Human 3h 3.33uM EID0009
Types Number Response transcription factors
Up-regulation 70 TSC22D3; SAP30; DAXX; IKZF1; DNAJC1; NR1D2; ZNF226; HOXC10; BMI1; LPIN2; ZIC1; PPARG; TRIM32; TERF2; SFMBT1; SMARCE1; SOX4; PPARGC1A; NR1H3; BASP1; ARNTL; MYT1L; CERS6; ID2; BRD8; TCF12; CEBPG; GFI1; TRIM22; OSR2; RBL2; PIAS2; SAP18; THAP10; AFF1; GTF3A; SMARCA2; BRD2; HOXB7; OLIG2; PTTG1; SREBF1; DEK; LMCD1; HOXC6; IRX5; TFEC; ELK3; CRYM; RBBP7; ZBTB18; TBX3; PIR; DACH1; TLE1; NPM1; HMGB1; RORA; IFI16; TXNIP; INSR; ZBTB38; HLTF; ELF1; GATA6; ARID5B; KLF2; ESR1; NR2F2; NFIL3
Down-regulation 152 MYC; TCERG1; HMGA2; ZNF551; ZBTB24; TSC22D1; ZNF134; EP400; PAXBP1; KLF6; ILF2; NR4A1; CEBPD; ZNF211; MLXIP; NR4A2; ZNF195; PLAGL2; YBX3; BAZ2B; ZFP36L1; ZNF593; EGR1; ZNF587; ZNF667; HMG20B; CIZ1; E2F5; FOSL1; TGFB1; ELF5; PBX3; SNAPC4; TP53; HOXD1; TAF4B; JUNB; BCL10; ZNF93; WT1; CREB3L2; SIX2; NR4A3; BARX2; CREB1; ZBTB7A; ATN1; INSM1; GFI1B; ZNF264; WWTR1; FOXA2; PLAGL1; NR0B2; ERG; ZNF562; CBFA2T2; TCF7L1; ZNF224; PPRC1; ZNF43; TEAD4; TRIB3; MED14; MNX1; HES1; PNRC1; BACH2; CCDC59; BCOR; PCGF3; MED21; ELF4; BNC2; ZNF426; ZNF652; ISL1; ARNTL2; MECP2; ID1; GATA1; NPAS2; RBFOX2; ZNF544; LZTS1; HMBOX1; ARNT2; SOX2; ZBTB20; MEIS2; CBX4; L3MBTL1; HOXD3; ZFHX4; GLI2; TSC22D2; JUN; REL; NANOG; ZNF665; PIAS4; ZNF177; KLF10; SNAI2; LIN28A; ZSCAN18; ZNF586; CITED2; NFAT5; BARX1; CREM; ZNF711; HIC2; MYCN; HDAC9; BCL11A; JUP; ZNF512B; PKNOX2; ADRB2; ETS2; HOXB13; FOSB; BACH1; ETS1; EYA1; PAX6; ZNF331; NFE2; ID4; HIRA; HEY1; ID3; TULP3; SOX9; ZFP36L2; SATB2; TCEA2; NFATC4; TCF7L2; HHEX; ST18; TFAP2C; TCF21; FOXG1; SALL2; SOX17; ZEB1; MYCL; NFATC3; EGR2; SOX11