Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16965 Azd-6482 GSE70138 MCF10A Human 3h 0.12uM EID0009
Types Number Response transcription factors
Up-regulation 29 FOXO1; KAT6B; KLF9; HIPK3; NCOA3; CD3D; NR1D2; TOPORS; TGIF1; FLI1; CITED2; BCL11B; BAZ1A; BCL6; MAFB; SSX1; ZNF83; TCEB2; KLF2; TXNIP; HTATIP2; RFX5; ZNF281; BACH1; NKX2-1; ASCL1; ELK3; EGR3; HOXC6
Down-regulation 26 PUF60; HSF1; SNAI2; TWIST1; HOXB6; BRD4; SOX10; JUN; HOXB5; E2F5; ATF3; MEIS1; CITED1; SATB2; FOXF1; BHLHE41; ARID5B; HEY1; BASP1; ID3; PBX3; TCF21; MEIS2; GATA2; TBX2; E2F2