Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16954 Azd-8330 GSE70138 MCF10A Human 3h 0.04uM EID0009
Types Number Response transcription factors
Up-regulation 66 SMAD6; ID2; TSC22D3; CHD8; ZSCAN18; ZNF274; ZNF304; TTF2; ZNF329; MED17; ZNF140; ZNF423; E2F8; ZMIZ1; JUP; OSR2; NCOA2; SSBP2; HOXD1; BTG1; ZNF217; ATF3; TXNIP; HMGN3; WT1; TLE4; SSX1; TULP3; ZNF623; ZNF273; HLX; INSR; SOX13; PLAGL1; ZNF107; MEIS2; SALL2; CERS4; BNC2; MYCN; NR5A2; ZNF415; ZNF467; TCF7L1; TRIB3; NANOG; TCF21; ZNF331; TFAP2C; MECOM; IRF9; NEUROD1; TWIST1; TRIM29; CTBP2; SNAI2; ZNF117; MYCL; ID3; GATA6; MEIS1; ARNT2; SOX17; ID1; PBX3; PEG3
Down-regulation 39 MYC; HMGA2; FHL2; NFKB1; FOSL1; EGR1; SPEN; MAFF; SOX9; CBFB; NKX3-1; EGR3; BAZ1A; PTRF; HIVEP2; SMAD3; RNF14; ARNTL; NR1D2; ELK3; HES1; JUNB; ZFP36L1; SMARCA1; RUNX1; BCL11B; ZBTB38; KDM5D; RUNX3; MED1; HMGA1; FOSB; LOXL2; THAP11; ELF1; EGR2; BASP1; SATB1; E2F2