Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16953 Azd-8330 GSE70138 MCF10A Human 3h 0.12uM EID0009
Types Number Response transcription factors
Up-regulation 17 TSC22D3; HMGN3; SOX4; TOB1; CD3D; ID2; BCL11B; TOX; MECOM; FOXJ3; MITF; HTATIP2; TLE1; HLTF; ATF3; PIR; ID1
Down-regulation 48 HMGA2; MYC; FOSL1; EGR1; TFEB; FHL2; ETV4; EGR4; BCL10; PPRC1; MAFF; KLF4; SPEN; NR2F1; ZEB2; FOXC1; EGR3; TP53; HMGA1; SATB2; TOX3; ZFP36L1; NFAT5; MYB; IRF6; TCF7L2; SCAND1; SOX9; DLX2; IRF8; KLF10; NFE2L3; BACH2; INSM1; SOX11; SOX13; GATA6; ETV5; HOXB2; FLNA; ELK3; TFAP2C; PBX3; EGR2; HHEX; ERBB4; PEG3; SATB1