Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16951 Azd-8330 GSE70138 MCF10A Human 3h 1.11uM EID0009
Types Number Response transcription factors
Up-regulation 27 NR3C1; TSC22D3; MED23; FOXJ3; DNMT3B; E2F8; TRIM22; EED; ZNF430; ZNF266; LMCD1; ID2; RBPMS; MAGED1; HMGN3; ZBTB18; HTATIP2; ELF5; BHLHE41; CITED2; TLE1; TRIM29; ATF3; SOX17; GATA6; MAFB; HOXC6
Down-regulation 34 HMGA2; MYC; EGR1; FOSL1; MAFF; ETV4; SOX9; PPRC1; BCL3; ZFP36L1; CREB3L1; HES1; HOXB7; HOXB6; JUNB; LOXL2; TGFB1; KDM5B; BHLHE40; HOXB2; NR2F1; KLF5; KLF9; TFAP2A; HOXB5; KLF10; ETV5; NPAS2; POU2AF1; HHEX; DACH1; ID1; EGR3; ERBB2