Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16950 Azd-8330 GSE70138 MCF10A Human 3h 3.33uM EID0009
Types Number Response transcription factors
Up-regulation 55 DNAJC1; IKZF1; MED23; TSC22D3; TLE4; ZSCAN31; UIMC1; TRIM22; TRPS1; PIAS1; PEG3; ITGB3BP; TOB1; ZMYND8; FOXL2; TFEC; VGLL1; GATA1; TRIM29; OSR2; RLF; RYBP; ELF5; TXNIP; PRDM2; CREB3L2; KLF4; TBX3; SOX13; ZNF721; KLF13; SNAI2; MITF; PLAGL1; ZNF467; TFAP2C; ZNF512B; CITED2; KAT2B; ID2; JAK2; NANOG; MAF; ZFP36L2; WT1; TOX; ZNF532; IRF8; MEIS1; KLF11; HIC2; NR1H4; CUX2; BASP1; MEIS2
Down-regulation 32 MYC; HMGA2; ZNF146; EGR1; SMAD3; FOSL1; ZFP36L1; POU4F1; MAZ; FLNA; HES1; CHD1; SIX1; PCGF2; RELA; WWTR1; THAP11; BAZ1A; ETS2; ZBTB18; HMGA1; CTNNB1; TGFB1; JUNB; SATB2; YWHAB; DLX2; ELK3; TAF10; NR2F1; SOX9; E2F2