Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16943 Ldn-193189 GSE70138 MCF10A Human 3h 10uM EID0009
Types Number Response transcription factors
Up-regulation 86 NFKBIA; RELB; TSC22D3; NR3C1; NFKB1; KLF6; ATF3; MAFF; FOSB; EGR1; XBP1; BHLHE40; HIVEP1; FOXO3; CDK7; NR4A1; DDIT3; ARID4B; HIVEP2; SMARCA1; TGIF1; KLF4; NFE2L2; LITAF; BCL3; CEBPD; FOXO1; SMAD3; MAF; PPARGC1A; ZSCAN18; BACH1; JUNB; RBPMS; ATF4; IRF1; GLI3; ETS2; NR4A3; NR4A2; CREBL2; HDAC9; HES1; NR3C2; TOX3; ZNF331; HBP1; RLF; CREM; FOS; SOX10; RYBP; ZNF226; BCL6; BTG1; BASP1; SPEN; NFIL3; CREB5; CREB3L2; REL; NKX2-1; PNRC1; PEG3; HOXD1; JUN; PITX1; CRY1; TCF21; TRPS1; ZNF217; TSC22D1; MAFB; BACH2; TLE4; TXNIP; GLI2; GATA6; NR1H4; TSC22D2; FOXF1; ID4; ELF1; EGR3; SOX9; SATB1
Down-regulation 49 CCNA2; MYC; FHL2; DEAF1; PRRX1; PTRF; CIZ1; TCEA1; NELFB; TRIP6; ZNF652; UBTF; NUP62; THAP7; CARM1; GTF3A; TAF1; MTA1; TRIM32; RNF141; PMS1; ZMYND8; PDLIM1; PRKDC; PEX2; ZKSCAN1; ZBTB38; TRIM16; HTATIP2; MYT1L; TGFB1; SCAND1; EYA2; CBX3; MEIS1; EHF; APEX1; CENPF; HOXC10; HOXB7; ID1; MECOM; THAP11; SUV39H1; LEF1; ERBB2; VPS72; TBX2; E2F2