Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16940 Cgp-60474 GSE70138 MCF10A Human 3h 0.37uM EID0009
Types Number Response transcription factors
Up-regulation 19 SMAD6; SP100; CARHSP1; ZMIZ1; STAT3; HOXC4; ZSCAN18; ENO1; TBX2; CNBP; SSX1; HDAC1; BCL11A; TAF10; HOXC10; JUP; FOXF1; ID3; TCF21
Down-regulation 104 MYC; HOXA5; PLAGL2; ADRB2; ADNP; FHL2; CDK7; ARID4B; HOXA10; NFKBIA; XBP1; HES1; CCNA2; NRIP1; MED17; ZNF574; SNIP1; ZNF146; CEBPB; MED23; TAF4; ZNF14; ZNF212; ZNF12; CHD1; TBP; ZBTB43; TSC22D3; CTCF; TGS1; ZNF410; TOB1; POLR3F; NR2F6; TGIF1; RNF111; ZNF443; ZFP36L2; NPAT; PPRC1; TOPORS; E2F3; RLF; SMAD7; CHD7; ZBTB16; FOXO3; ZNF267; SERTAD2; KLF6; JUND; HOXA11; HOXA1; FOXO1; TRIM22; TLE1; ZBTB18; TBPL1; ZFP36L1; BTG1; TRIM32; NRBF2; ABL1; EED; CEBPG; SAP30; SATB2; KAT6A; ZNF22; USP22; SALL1; ZNF281; RNF4; HSF2; BAZ1B; KLF10; TAF1D; NUP62; TSC22D2; BHLHE40; FOSL1; HMGB3; ZNF217; BRD2; TSC22D1; MTF2; BAZ1A; ZNF516; EGR1; ETS2; ELF1; IRX5; NFIL3; AFF1; SUV39H1; ELK3; ESR1; CBFB; STAT4; KLF2; SMARCA2; TRPS1; JUN; EGR2