Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16921 Gsk-1059615 GSE70138 MCF10A Human 3h 1.11uM EID0009
Types Number Response transcription factors
Up-regulation 38 TSC22D3; SOX4; TXNIP; SMARCC2; HBP1; CALCOCO1; HDAC6; OSR2; FOXO1; NFE2L1; AEBP1; CARHSP1; ATF4; ZBTB16; ID2; PBXIP1; ZNF160; AES; PNRC1; MXI1; CREBL2; RFX5; HMGN3; MAF; FOXN3; TP63; BNC2; BCL6; ZNF532; MAFB; KLF4; BTG1; ZIC1; TCF4; JUN; ZFPM2; ZBTB20; BASP1
Down-regulation 30 NR2F6; HMGA2; BHLHE40; HES1; EGR4; XBP1; CHD7; NUP62; FOSL1; E2F5; SPEN; FOXC1; EGR1; PITX1; BAZ1A; CTR9; EGR3; EMX2; CEBPZ; FOXF1; HDAC9; SATB2; TOX; ADRB2; NFE2; JARID2; MEIS1; ELK3; POU2AF1; SOX9