Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16920 Gsk-1059615 GSE70138 MCF10A Human 3h 3.33uM EID0009
Types Number Response transcription factors
Up-regulation 44 TSC22D3; HOXA5; NR3C1; SOX4; ID2; ARRB1; CARHSP1; ZBED1; RNF10; HBP1; FOXN3; PRKDC; RSF1; FOXO1; FOXO4; EZH1; SMAD6; ZBTB16; DNMT3B; MECOM; TXNIP; LITAF; CEBPD; IRF7; NCOA2; PBXIP1; TCEB2; BRD8; EZH2; MAFB; JUP; AFF1; ZNF217; MAF; TLE1; MXI1; LPIN2; ZIC1; CTR9; PITX2; ZNF532; DACH1; THAP11; HOXC6
Down-regulation 47 HMGA2; TAF9; CCNH; PPRC1; FHL2; FOSL1; MYC; CREB1; CCDC59; TBP; KLF10; PATZ1; ADRB2; TAF1A; SF1; ZNF593; PTRF; XBP1; MAFF; SMAD1; ZFHX4; HES1; EGR1; PROX1; ZNF652; SALL1; BCL3; CEBPZ; EGR3; RYBP; BHLHE40; SOX9; PITX1; ZNF516; ZFP36L1; ISL1; ZBTB18; HIRA; CBFB; MAGED1; SFPQ; EMX2; AHR; ZFP36L2; NFE2; HHEX; LEF1