Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16887 Geldanamycin GSE70138 MCF10A Human 3h 0.12uM EID0008
Types Number Response transcription factors
Up-regulation 31 RELB; GATA2; KDM5A; DDIT3; ZNF589; NFE2L1; XBP1; SPIB; KDM2A; HMBOX1; IRF4; BCL3; BRD4; TAF9B; ZNF165; ZIC1; NKX2-2; PAX6; ZNF532; NR0B1; PIR; RUNX3; TCF4; PBX1; TWIST1; IRF7; HOXB7; CREB1; MSX1; SMAD1; MEIS2
Down-regulation 39 MYC; HES1; HMGA2; FOSL1; ADRB2; NFKBIA; EGR1; TSC22D3; NFIL3; CEBPD; ABL1; VGLL4; TGIF1; ZFP36L2; ETS2; RUNX1; KLF2; ELK3; TOX3; EGR3; NFE2; BAZ1A; HIC2; MNDA; TXNIP; HMGB3; KLF6; TLE1; LYL1; FOSB; ELF3; NR4A2; NKX3-1; ID4; BCL11A; ZBTB18; PBX3; ATF3; CEBPA