Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16879 Radicicol GSE70138 MCF10A Human 3h 1.11uM EID0008
Types Number Response transcription factors
Up-regulation 55 KDM5A; ZMIZ1; ZNF473; AFF4; FOXO4; ARID5B; BRD8; NR1D2; XBP1; DDIT3; SMAD6; MAFB; PIR; ZNF410; ANKRD1; BAZ2A; SOHLH2; GATA3; BAZ2B; SSX1; CNOT1; RUVBL2; ZNF165; ZNF266; CALR; MYCN; BATF3; LIN28A; AGO2; NFAT5; PITX2; ZNF217; CHD3; ASCL1; MTF2; POU4F1; PPP1R13L; PLAG1; TWIST1; MKL2; DLX2; BRD2; ZSCAN18; KDM5D; TLE4; BCL11B; NKX2-2; FOXG1; FOSL2; TOX; MAGED1; BHLHE41; SSBP2; ID4; HOXC6
Down-regulation 77 MYC; HES1; HMGA2; SUZ12; NFKBIA; CEBPD; ESRRA; ADRB2; APEX1; TP53; MED24; NR4A2; EGR1; ETS2; TERF2; ABL1; MLLT10; HOXB5; ZNF273; JUNB; C1QBP; RNF138; MEIS1; TSC22D1; ZNF43; CHD9; PAXBP1; ZNF394; FUBP1; ACTL6B; ZNF536; ZFP36L1; ZNF195; ZNF611; ZFPM2; TFCP2L1; FOSB; NR5A2; TOB1; ZNF224; ARNTL; NAB1; FOXN3; KLF5; OSR2; HIRA; ZNF160; ZNF652; CCNC; NR4A1; KLF6; ZNF430; BCL3; EGR2; HLX; HIC2; BHLHE40; CTBP2; SOX2; NR2F1; CRK; FOXF1; ZNF331; NR4A3; SOX11; ZKSCAN1; TLE1; EGR3; BASP1; CITED2; FOS; ARNT2; SOX9; PAX5; WT1; CEBPA; PAX8