Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16873 Withaferin-a GSE70138 MCF10A Human 3h 1.11uM EID0008
Types Number Response transcription factors
Up-regulation 81 ZNF274; ID2; GABPB1; EGR1; TRIM24; SFMBT1; ZNF473; SETD2; DLX2; NCOA6; RCOR3; NKX2-1; SFPQ; ELF1; ZNF266; CAMTA1; TTF1; HMGN3; ATF7IP; CREB3L2; HIVEP1; TMF1; ZSCAN31; KLF2; FOSB; KDM2A; ZNF329; DDIT3; ARID5B; PSMC3IP; ZNF165; EGR4; HSF2; HOXC4; NFAT5; MTDH; EYA2; JUNB; YAP1; HMGB1; KAT7; NR4A2; CHD7; RAD21; NCOA2; BLM; DDX5; SERTAD2; ZNF443; RBM39; YBX1; MSX1; PIR; NR1D2; ATF4; PHIP; BCLAF1; IRX5; SMAD6; HOXA1; AEBP1; CTNNB1; HMBOX1; AFF1; ATF3; RREB1; HOXC6; MAGED1; BRD2; EGR3; DNMT3B; MYT1L; NR4A1; AHR; ZBTB18; CRYM; ID4; ESR1; MEIS2; ID1; LEF1
Down-regulation 86 MYC; TFAP2A; HES1; HOXA10; HMGA2; ADRB2; UBE2L3; NFIL3; ZNF324; NFKBIA; CHD9; ZBTB7A; BASP1; CBX6; ZNF692; GTF2I; IRF8; MYCL; ETS2; APEX1; PLAGL1; VDR; IRF9; BRD4; TRIB3; ABL1; TBL1X; ZKSCAN1; TRIM22; PCGF3; ZNF665; WWC1; HIPK2; HOXB5; HOXB2; NAB1; ZNF467; ZNF124; ZBTB16; SOX9; ZNF611; HDAC9; ZNF22; BCL6; TRPS1; JUP; HOXA5; SIX3; SMAD1; ZEB1; FOXN3; CRK; RYBP; ZIC1; RBPJ; NFE2; TCF4; TRIM29; HIC2; LMCD1; TFEC; TRIP6; FOXF1; SOX4; ZNF91; SOX11; BCL11A; TSC22D1; ARNT2; MECOM; MNDA; KLF9; KLF11; ZNF652; PBX1; KLF4; ASCL1; TOX3; HEY1; EMX2; CREB1; SSBP2; PAX5; MYRF; CEBPA; PAX8