Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID16872	Withaferin-a	GSE70138	MCF10A	Human	3h	3.33uM	EID0008

Response Information :

Types	Number	Response transcription factors
Up-regulation	127	GATA2; GABPB1; ZNF274; ZNF552; MED23; ZNF432; ZNF586; ZNF468; HSF2; JUN; ZNF473; ATF3; TCFL5; TBPL1; DDIT3; PIAS2; ZNF14; EZH2; TBX3; ZMYM2; ZNF304; ARID4A; ZNF222; ING3; SETD2; TBP; ZNF134; REST; FOXC1; PKNOX1; ZNF528; NFAT5; FOXO4; SSBP2; ZNF83; SMARCD3; ZNF273; ZNF211; ZNF419; ZSCAN18; HLTF; ZNF264; STAT2; ZNF587; ZNF136; XBP1; HOXC4; CIR1; TBX2; ZNF331; IRF4; PAX8; NR1H3; ZNF430; CHD1; OSR2; BAZ2B; TLE4; CCDC59; ZNF710; EGR1; PHIP; RNF141; MAGED1; TP63; UBE2B; CIITA; ZNF248; TEAD1; SOX10; MTF2; SMAD6; TRIM28; ZNF175; HIVEP2; TGIF1; ZNF107; ZNF266; SMAD5; NCOA2; ZNF329; IL16; ZNF551; FOXD1; PIR; CTNNB1; SP140; HSBP1; CITED2; HOXC6; JUP; FOS; SMARCA2; FOXE1; TSC22D1; BCLAF1; IRF7; ERBB4; TFEC; TXNIP; HBP1; RYBP; BHLHE41; LYL1; CALR; ZNF544; MITF; NFATC4; IRX5; GATA3; BRCA1; HOXC10; FOSB; KDM5D; CEBPA; HOXB6; WT1; NR4A1; ARID5B; EMX2; PEG3; BASP1; POU2AF1; TFAP2C; ESR1; LEF1; ID4
Down-regulation	102	MYC; ADRB2; HES1; TFAP2A; HOXA10; NFKBIA; NR1I2; FOXK2; BRD4; ZNF232; HMGA2; PRMT2; CUX2; MAFF; MNT; ATF5; ZIC1; TRIB3; MAFG; CHD7; CHD4; TSC22D3; YAP1; ZBTB16; KDM4C; TERF2; SUPT3H; HDAC9; HNRNPD; CAPN15; TWIST1; XRCC6; FOXI1; CAMTA2; SOX11; ZBTB7A; TGFB1; MYBL1; CREBL2; KLF7; C1QBP; SMAD3; HOXA5; NCOR2; ETS2; SATB2; ZNF281; FOXN3; DDX17; ZNF589; NFIL3; PRPF6; ZNF22; TERF1; CNBP; TCF7L2; WWTR1; DACH1; GATA6; NR5A2; FOXA1; YWHAB; FOXG1; ZFHX4; KLF2; PPP1R13L; CEBPB; SOX13; INSM1; SCAND1; ERG; NFE2L3; ZHX2; PAX6; TOX3; KLF11; SMAD1; MEIS2; PBX3; ZNF423; SHOX2; THAP11; ELK3; CRK; NFIB; SOX9; TLE1; FOXF1; KLF9; BCL11B; SATB1; INSR; CREB1; RUNX3; ARNT2; AEBP1; BHLHE40; MXI1; MYB; MAFB; HEY1; IKZF1