Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16871 Withaferin-a GSE70138 MCF10A Human 3h 10uM EID0008
Types Number Response transcription factors
Up-regulation 63 NR1H2; ID2; DDIT3; EGR1; ING3; NR1D2; BAZ2A; XBP1; ZMYM2; FOS; TSG101; JUN; ZNF444; ID3; KMT2B; CCNC; POLR3C; BACH1; ATF4; BPTF; TLE4; ISL1; PDLIM1; TRIM22; ZNF22; MED14; JUNB; ATF3; BTG1; NR4A1; IRF7; KLF10; PITX2; HBP1; ID4; EGR3; KAT6B; BRCA1; TP63; IRF8; FOSB; ZFHX4; SSX1; TAL1; ZNF331; TFAP2C; TBX3; KLF2; BCL6; CREB1; ZFPM2; NR4A2; TWIST1; BHLHE40; MSX1; ID1; LEF1; TRIM29; FOXG1; EGR2; SOX11; PBX1; MAFB
Down-regulation 37 MYC; HES1; IKBKAP; LHX1; NFKBIA; STAT3; MAFG; TOX3; ADRB2; BMI1; CENPB; LITAF; NPAS2; INSM1; ZNF160; YWHAB; PEG3; WWTR1; RBBP4; SOX13; ZNF91; COPS2; MLXIP; ZNF721; EYA2; NR0B1; HOXA5; MKL2; ZKSCAN1; TRIM16; HMGB2; FOXO1; CRK; SATB1; ZIC1; GATA6; PAX8