Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16870 Mitoxantrone GSE70138 MCF10A Human 3h 0.04uM EID0008
Types Number Response transcription factors
Up-regulation 46 ID3; TGFB1I1; ID1; ZNF467; SOX13; FOXF1; TBX2; IFI16; BCL3; MEIS2; TRIB3; CBFA2T3; BRCA1; HLF; HEY1; BHLHE40; FOXG1; LITAF; TBX3; TCF4; ZNF264; INSM1; HOXB2; REL; ESR1; EYA1; ISL1; INSR; IRF4; ARID5B; SOX2; ATF3; JUP; TCF21; HLX; ZNF423; ZFP36L1; PITX1; MXI1; ARNT2; EMX2; HOXD1; ZHX2; POU2AF1; MECOM; CREB1
Down-regulation 27 HMGA2; ZNF84; E2F3; BLM; YAF2; HOXA7; MYBL1; RNF14; NFIB; CENPF; ING2; BATF3; HSBP1; ZIC1; PITX2; BASP1; SATB1; PURA; HMGB3; ZBTB38; MAGED1; WWC1; AFF1; SOX4; SAP30; HOXC6; CEBPA