Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID16869	Mitoxantrone	GSE70138	MCF10A	Human	3h	0.12uM	EID0008

Response Information :

Types	Number	Response transcription factors
Up-regulation	52	ZNF571; NFKBIA; ZMYM2; ZNF254; ADNP2; RORA; PMF1; SREBF1; HOXD11; POU4F1; MED24; MEOX2; KAT6A; PBXIP1; HMGB1; ETV5; SUB1; SMAD7; SSX1; PDLIM1; FOXG1; EN1; IRF1; FOSL2; SHOX2; BACH2; CAMTA1; NKX2-1; NR0B1; RBL2; CITED1; HHEX; TCF4; BCL11B; POU2AF1; EGR1; MSX1; IRF4; AES; KLF11; KLF4; NR4A3; LEF1; MAGED1; IRF8; NR4A1; BHLHE40; KLF10; AEBP1; SOX11; HOXB2; HOXC6
Down-regulation	64	USP22; STAT3; FUBP1; ENO1; SOX9; BRD8; WWTR1; NFIB; ZNF430; SIM2; CBX6; MEIS1; ETV1; ZNF665; ZNF189; RFX5; FOXC1; CTBP2; BRCA1; ZNF175; NR2F1; TRPS1; BCL11A; RUNX1; AHR; AGO2; ZKSCAN1; YWHAB; MYBL1; ZNF160; IFI16; HMGA1; PHIP; PEG3; HTATIP2; LITAF; ZNF721; TSC22D1; TRIB3; TBX3; ERG; CENPF; PBX3; SMARCA2; LYL1; ZHX2; BAZ1A; BASP1; ERBB4; INSR; CRYM; TRIM29; NR2F2; ELF5; CRK; GATA6; ZEB1; SATB1; MYRF; FOS; GATA3; E2F2; PAX8; CEBPA