Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID16867	Mitoxantrone	GSE70138	MCF10A	Human	3h	1.11uM	EID0008

Response Information :

Types	Number	Response transcription factors
Up-regulation	54	ZNF274; NFKBIA; RELB; IRF1; ZSCAN18; FOXJ1; FOXO3; JUN; FOSB; HHEX; ATF3; POU5F1B; ATF5; EGR1; IRF7; ZFPM2; MYF6; TCFL5; CCDC59; DDIT3; FOXE1; ZNF423; BCL3; TOB1; NR4A1; JUP; MAGED1; NKX2-1; PAX8; PSMC3IP; KLF11; ZNF331; SSX1; NANOG; ERBB4; IRF4; TGIF1; CIITA; EYA1; ID3; ID4; PBX3; BNC2; ZNF91; NKX3-1; WT1; OSR2; BHLHE41; ZBED2; TXNIP; CREB1; EGR2; MEF2C; EMX2
Down-regulation	71	MYC; HMGA2; FHL2; RCOR1; HOXA10; ARID4B; ERF; NFIL3; ADRB2; CEBPB; ZBED4; CNOT6; NR3C1; ZNF281; ZBTB16; CENPF; KAT6A; RBBP5; MBD2; NLK; MAML1; FOXK2; BAZ2B; TAF4; CHD3; ZNF189; ZNF573; ZFP36L2; AGO2; TRPS1; ARID1A; ZKSCAN1; CLOCK; TGFB1; PITX1; TBL1X; PAX6; SATB2; SAP30; YWHAB; DACH1; SMAD7; MYBL1; CUX1; PCGF2; TBX3; RREB1; NRIP1; BCL11B; FOXF1; CRK; TOX; BAZ1A; ELK3; FOXA1; ETS2; NFIB; INSM1; ZBTB38; TRIP6; RUNX3; MEIS1; SMAD1; SOX9; BHLHE40; GATA6; MSX1; HOXC6; HEY1; SATB1; CEBPA