Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16866 Mitoxantrone GSE70138 MCF10A Human 3h 3.33uM EID0008
Types Number Response transcription factors
Up-regulation 36 EMX2; NAB1; FOXJ1; RELB; JUN; EGR1; ZFPM2; HAND1; ATF3; PFDN5; RBFOX2; PTTG1; CSDE1; SMARCD3; HSBP1; NPM1; HMGB1; BHLHE40; PAX8; HDAC9; MITF; YBX1; HOXD3; MECOM; ZBED2; ZNF423; OSR2; FOSB; CEBPA; AEBP1; EGR3; SMARCA1; HEY1; WT1; HOXC6; ID4
Down-regulation 74 MYC; FOSL1; FHL2; ADRB2; HMGA2; CCNA2; NCOA3; SMAD3; HOXA10; NFIL3; ZMIZ1; CEBPD; CHD8; TAF5; MYBL1; ADNP; NFYA; ZNF3; APEX1; ZNF721; ZNF84; ZNF160; RNF111; TSC22D2; ZNF232; IRX5; ZNF44; IRF9; YAP1; CHD7; PAWR; CBX4; ZNF611; ARID1A; SCAND1; TBL1X; TOPORS; MNDA; NKX3-1; TOX3; ZNF587; TFEB; SATB2; CEBPB; E2F5; KLF7; TAF1D; FOXD1; ZBTB16; RUNX1; SOX4; WWTR1; TCF7L2; VDR; ERG; ZNF652; FOXA1; BMI1; FOXO1; BCL11B; BTG1; CRK; ZKSCAN1; PITX1; RUNX3; POU2AF1; FOXF1; MYB; ZEB2; MYRF; SAP30; MSX1; FOS; IKZF1