Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID16865	Mitoxantrone	GSE70138	MCF10A	Human	3h	10uM	EID0008

Response Information :

Types	Number	Response transcription factors
Up-regulation	74	SUV39H1; ZMIZ1; ZNF274; LIMD1; HOXC11; NFE2L3; HAND1; HDAC9; NFKB2; KLF15; JUN; CD3D; TCF20; CBX6; RBPMS; ARID5B; AIP; PQBP1; HOXC4; ACTL6A; CREBL2; BHLHE41; BRCA1; CALCOCO1; CALR; CITED2; ASCL1; ZMIZ2; BCL11A; NR1H3; ZNF580; KDM5D; MYCN; PAWR; TRIM22; E2F8; ING4; ERBB4; CBX7; TP63; SSX1; REPIN1; CITED1; SOX9; TRIM29; BCLAF1; ATN1; FOXE1; PAX8; TFEC; ELF3; IFI16; PRRX1; HOXC6; ZIC1; HOXC10; MECOM; WWC1; SOX4; VPS72; LYL1; NR2F1; FLI1; CEBPA; ZBED2; FOXF1; MNDA; EMX2; ID4; NR2F2; SSBP2; BHLHE40; MAFB; ATF3
Down-regulation	144	MYC; FOSL1; NFKBIA; ADRB2; ABL1; TSC22D2; ARID4B; CEBPD; FHL2; SERTAD2; NFE2L1; HOXA10; CHD7; NR3C1; DR1; RNF138; ZNF3; RORA; SNIP1; HMGA2; ZNF410; MYBL1; FOXK2; PLAGL2; CCNA2; NR4A3; RYBP; TWIST1; CHD1; E2F3; TCF3; BRWD1; TEAD3; BCL10; MAFG; CTCF; TFAP2A; HES1; RLF; HMBOX1; BAZ2B; ZBTB11; MED17; FOXD1; PRKDC; CRY1; ZNF10; MTF2; VEZF1; ZNF571; DDIT3; MEOX2; CHD9; RRN3; MTDH; ADNP2; FOXM1; SF1; HIVEP1; ZNF292; SHOX2; ZNF189; THAP4; MGA; REL; ZFX; HOXA5; HMGB2; ZNF12; ZNF131; TLE1; SKIL; CEBPB; RNF111; KAT6A; ZBED1; CAMTA1; SMAD3; WWTR1; TAF1A; CEBPG; SIX2; DACH1; TMF1; SMAD7; ZNF232; ZNF281; FOXO1; ZSCAN31; EGR4; ERG; CUX2; ID3; BACH2; ZNF195; NR4A2; IRX5; PAXBP1; ZFP36L2; KLF11; HTATIP2; ZNF43; ZNF165; ATF4; TAF1D; FOSL2; ISL1; RBM39; FOXJ3; ZBTB16; CCNE1; SATB2; ZNF117; SFPQ; ID1; KLF10; ETS2; LOXL2; ZNF331; CUX1; RREB1; ZNF423; HLX; ELF1; ST18; IRF7; SOX11; JUND; RUNX3; CENPF; BTG1; ZBTB20; ELK3; ZFP36L1; PLAGL1; AHR; MSX1; ZEB2; PBX3; TLE4; AEBP1; INSM1; BASP1; GATA6