Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16862 Brivanib GSE70138 MCF10A Human 3h 0.37uM EID0008
Types Number Response transcription factors
Up-regulation 40 ID2; E2F8; NFE2L1; PBXIP1; MBD4; CERS4; CITED1; IRF8; WDHD1; MED13; SPIB; ETV5; PITX2; MED14; VPS72; BRIP1; SHOX2; TTF2; HIC2; POU2AF1; TWIST1; NFE2L3; BASP1; SOX11; FOXO1; TRIP6; GATA3; HHEX; FOXF2; KLF10; TCF4; NANOG; ZKSCAN1; MECOM; SOX9; PBX1; BHLHE41; TFAP2C; MEIS2; CRK
Down-regulation 50 ING3; TBPL1; NPM1; PTTG1; PA2G4; ID3; NR1D2; SIM2; YBX1; CNBP; HMGB2; ELK3; BBX; LMCD1; FOSB; RBM39; SOHLH2; DACH1; HTATIP2; FOXC1; FOXJ3; FOXN3; GTF3A; TGIF1; KAT6B; HMGN3; TRIM29; SNAI2; ZNF281; CREM; TXNIP; MAF; MLXIP; AHR; JUND; KLF2; AFF1; KLF5; BCL11B; LEF1; ID1; SATB1; EMX2; HOXC10; NR4A2; AEBP1; HOXC6; ID4; PAX8; CEBPA