Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16859 Brivanib GSE70138 MCF10A Human 3h 10uM EID0008
Types Number Response transcription factors
Up-regulation 60 ZFY; MEF2C; ZFP69B; KDM5D; FOXN3; TBX1; NEUROD1; TGIF2; ZNF239; ZNF444; HMGN3; SNAPC4; PRDM10; TGFB1; ZNF623; PRDM2; RBPJ; ZNF512B; NR1H4; NKX2-2; CUX2; KLF11; PCGF3; IRF9; BRD4; HIC2; TRIM24; EGR2; ZNF573; TWIST1; E2F8; SOX10; SALL2; AR; NFATC4; TRIB3; TEAD4; HLF; HDAC9; BRD2; IRF8; FOXF2; ID1; CEBPA; HHEX; PAX6; TFAP2C; ZNF264; SATB2; CREB1; SOX11; NKX3-1; RUNX3; ARNT2; HOXD1; INSM1; MXI1; TCF4; SMARCA1; FOS
Down-regulation 36 TBPL1; ARID4B; CREG1; ITGB3BP; HMGA2; TOB1; ZSCAN31; RBBP7; TGIF1; BAZ2B; HOXB7; TRIM29; ELF3; ATF1; ETS2; LITAF; TRIM16; HOXB6; SATB1; CTBP2; TSC22D1; MKL2; EGR1; SAP30; PIR; ZNF652; TCF7L2; MAGED1; ZBTB18; EYA2; HOXC6; JUP; HOXB2; ATF3; BHLHE40; MAFB