Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16846 Linsitinib GSE70138 MCF10A Human 3h 0.04uM EID0008
Types Number Response transcription factors
Up-regulation 56 MED17; SUMO1; ZNF500; IRF9; CDK9; SALL2; TRIB3; PIAS1; ID3; ZNF623; FOXM1; ING4; ZNF43; HBP1; TCF7L1; ZNF331; ZNF329; ZNF423; TULP3; ZEB1; NFIC; RAD21; CUX2; ZBTB16; PNRC1; SOX11; KLF13; ZNF117; ARNT2; NFATC4; SOX2; CREB1; BRD4; NKX2-1; ZNF467; TCEA2; SMAD1; EYA1; PBX3; TWIST1; ZFP36L2; MEIS2; HOXD1; TCF4; HLX; ARID5B; ZHX2; TRPS1; KLF11; MECOM; SOX17; AEBP1; ID1; NR4A2; TFAP2C; FOS
Down-regulation 25 XBP1; HMGB3; HLTF; PURA; HOXB7; BCL3; JARID2; ELF1; BASP1; BMI1; RNF14; SATB2; PIR; BHLHE40; SMARCA2; EGR1; SMAD7; HOXC10; ZBTB38; TOX3; SATB1; HOXC6; ZEB2; MAFB; CEBPA