Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16845 Linsitinib GSE70138 MCF10A Human 3h 0.12uM EID0008
Types Number Response transcription factors
Up-regulation 45 GATA2; ZNF274; TSC22D3; ING3; TADA3; HIVEP2; IRF5; BRD8; DEK; IFI16; NCOR2; BCLAF1; YBX1; HLTF; DDX5; TBX2; KLF10; BMI1; SMARCA2; FOXC1; MBD2; PPARGC1A; BHLHE40; BASP1; ZIC1; SAP30; ZBTB16; BRD2; BHLHE41; IRX5; CEBPA; HOXB6; AFF1; HOXC10; AHR; SMAD7; TXNIP; HOXC6; RXRA; NR2F2; PIR; KDM5D; ID1; MAFB; CRK
Down-regulation 49 SUZ12; ZNF146; YAP1; ZNF500; ZBTB20; NFKB2; ZNF117; TRIB3; NFE2L3; ZNF611; ZNF573; ZNF423; CERS4; ZNF160; TCF7L2; HMBOX1; HIRA; PIAS1; NFAT5; CARHSP1; ZNF264; ZNF43; LIN28A; NFATC4; SATB1; ZNF721; HIC2; TULP3; SOX9; BACH2; NANOG; GATA6; MEIS2; TCF7; MYRF; ZNF91; ST18; MXI1; WWC1; TCF21; FOXF1; ZEB1; TWIST1; ARNT2; BCL11A; ATF3; FOS; IKZF1; PAX8