Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16844 Linsitinib GSE70138 MCF10A Human 3h 0.37uM EID0008
Types Number Response transcription factors
Up-regulation 35 TSC22D3; E2F2; HIPK1; BTG1; FOXO4; JUP; ERBB2; GATA3; OSR2; CITED2; JAK2; PNRC1; NANOG; BASP1; ZNF264; TOB1; MEOX2; FOXO1; ZNF217; IRF4; LYL1; ZNF423; ZNF652; MYB; KLF2; INSR; TXNIP; ESR1; POU2AF1; NR2F2; MEIS2; PAX5; ARNT2; ZNF91; PBX1
Down-regulation 20 ZNF302; JUN; DMTF1; DACH1; TRIB3; BHLHE40; LEF1; MYBL1; SATB1; ELK3; NKX3-1; TBX3; NR2F1; TOX; EGR3; KDM5D; EGR2; HEY1; CEBPA; PAX8