Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16843 Linsitinib GSE70138 MCF10A Human 3h 1.11uM EID0008
Types Number Response transcription factors
Up-regulation 45 TSC22D3; ADRB2; BTG1; NR3C1; KDM5B; ATF7IP; GLI3; KDM4C; CNOT6; FOXO1; LYL1; GFI1; TERF2; PIAS1; JUP; ID3; IKZF1; VEZF1; RBM39; ZNF430; ID2; ZMYND8; ERG; KLF2; MYB; BCLAF1; KAT6B; HHEX; TOB1; BCL11A; POU4F1; PAX5; JUNB; CITED2; BACH2; BASP1; SMAD1; AEBP1; FOSB; COPS2; ZNF423; ZKSCAN1; CRYM; CREB1; FOS
Down-regulation 76 FOSL1; BRDT; LZTS1; E2F3; SOHLH2; NKX2-2; DNAJC2; ZNF571; ZNF529; ZNF177; ZFP69B; ZNF516; ZNF223; ZNF329; ZNF415; ZNF667; TSC22D2; PGR; ZNF165; KMT5A; ZNF83; SCAI; ZNF10; ZNF239; EGR3; SALL2; CDK9; TRIM24; SKIL; STAT1; NCOR2; PHOX2B; FOSL2; ZNF682; CAMTA1; GATAD2A; JUND; IRF9; ZNF331; PEG3; ZNF512B; CEBPB; WWTR1; FOXG1; SALL1; ISL1; ZSCAN18; BHLHE41; NR0B1; VPS72; DLX2; NFE2; NKX2-1; CREM; TBX3; NR4A3; ZFP36L1; GTF3A; EGR2; WWC1; DACH1; MEIS1; ESR1; TFAP2C; HOXC10; MSX1; ID4; SOX17; BHLHE40; EMX2; HEY1; LEF1; ATF3; ZNF586; PAX8; CEBPA