Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16842 Linsitinib GSE70138 MCF10A Human 3h 3.33uM EID0008
Types Number Response transcription factors
Up-regulation 41 TSC22D3; PBXIP1; NCOA2; CDX2; LYL1; NR3C2; HMGB3; WNT4; JUP; CDX1; GFI1B; MXD4; TULP4; ZNF160; BTG1; IRF8; IKZF1; CTBP2; ARNTL; HBP1; PLAGL1; ASCL1; TBX3; ZBTB38; MYB; IRF7; BASP1; ZNF611; BCL11A; TCF7L2; PAX5; HOXA5; CRYM; POU2AF1; OSR2; CEBPA; RUNX3; TCF4; INSM1; MXI1; FOS
Down-regulation 31 FOSL1; LZTS1; E2F6; RNF6; GTF3A; BACH1; SOHLH2; EGR4; NR1D2; PEG3; FOXG1; SATB1; ISL1; NRBF2; BRD2; FLNA; ELF5; DLX2; NKX3-1; ZNF512B; ELK3; DMTF1; DLX5; JUND; BHLHE41; EGR2; SOX11; BHLHE40; ATF3; MAFB; PAX8