Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID16841	Linsitinib	GSE70138	MCF10A	Human	3h	10uM	EID0008

Response Information :

Types	Number	Response transcription factors
Up-regulation	51	TSC22D3; MEF2C; NFE2L1; ID2; TCF4; TTF2; FOXN3; BPTF; CREBL2; ZBTB16; E2F8; KLF2; HBP1; PRRX1; AHR; ZNF532; ARID5B; TP63; ERBB2; RBPJ; INSR; VPS72; SOX9; CEBPB; SOX11; CTBP2; FOXC1; ERBB4; FOXG1; FLI1; PNRC1; KLF4; BCL6; HIPK3; ZNF512B; KLF9; TFAP2C; KLF11; TLE4; NFIB; TWIST1; JAK2; CREB1; SMAD1; BCL11A; TRIM29; MXI1; ARNT2; MAFB; PBX1; EMX2
Down-regulation	33	HOXA5; UBP1; FOSL1; TFDP2; IRF1; ELF4; BCL11B; STAT4; ZNF44; JUN; LEF1; DNMT3B; RLF; HOXB2; POLR2A; CREM; PTTG1; LITAF; ASCL1; BHLHE40; SATB1; PEG3; CD3D; CRK; EGR2; MYBL1; TOX3; EYA2; ATF3; MSX1; WT1; CEBPA; PAX8