Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16840 Ruxolitinib GSE70138 MCF10A Human 3h 0.04uM EID0008
Types Number Response transcription factors
Up-regulation 56 GATA2; ZNF274; E2F2; DEK; SOX5; PAX2; EYA1; FOXJ1; ZNF266; FOXC1; IRF5; TBX2; SSX1; TTF2; POU4F1; MEOX1; PHOX2B; ZSCAN18; HOXB6; PAX8; TAF9B; SOHLH2; MEIS1; HOXD3; ID3; SMAD6; YBX1; SALL1; TXNIP; ISL1; ZBED2; MECOM; ZIC1; ELF3; SNAI2; HIPK3; NR2F1; TSC22D1; SOX17; FOXG1; HOXB7; ELK3; ID4; ERBB4; SOX11; OSR2; TCF21; MAGED1; CREB1; KLF4; NKX3-1; WT1; EMX2; HOXB2; ID1; ATF3
Down-regulation 30 UBP1; TGFB1I1; ZNF44; SP140L; MAFF; PIAS4; NR2F6; TCF7; INSR; TWIST1; ZNF160; REL; IRF7; ZNF281; TRIM22; RORA; ZNF721; MYB; TGFB1; ZNF611; IRF8; MYBL1; CRK; ZKSCAN1; IRX5; POU2AF1; ESR1; FOS; MEIS2; CEBPA