Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16839 Ruxolitinib GSE70138 MCF10A Human 3h 0.12uM EID0008
Types Number Response transcription factors
Up-regulation 61 GATA2; HOXA10; E2F2; BRCA2; HOXA11; NFIX; NEUROG2; PGR; ZNF516; TP73; CSDC2; RBL1; E2F8; AR; HDAC1; PAWR; MSC; ABL1; TBL1X; MED14; CREB3L1; ASCL1; JUN; TGFB1I1; NR1H4; WT1; CERS4; BRCA1; LYL1; EYA1; PITX2; FOXA2; SPIB; RORA; ELF3; BTG1; SOX13; KLF6; OLIG2; FOSL2; JUP; HLF; TCF21; NR0B1; ZFP36L1; AEBP1; FOSB; MYB; SOX9; PLAGL1; INSR; MXI1; CREB1; FOXG1; ESR1; TXNIP; PBX1; PEG3; EGR3; PITX1; MEIS2
Down-regulation 43 HTATIP2; ARID4B; CREB3L2; ZIC1; KDM5D; CHD7; NR1H3; PSIP1; LITAF; BACH1; NCOA2; CRY1; BCL6; TP63; MKL2; HOXB7; RREB1; ATF1; TLE1; ZFP36L2; NRIP1; ZNF512B; HLTF; CTR9; AHR; HMGA1; BASP1; SOX10; FOXC1; TOX; ZBTB38; TRIM16; TBX3; DNMT3B; ELK3; TRIM29; ZEB1; NR2F1; SMARCA1; TCFL5; ATF3; LEF1; IKZF1