Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16838 Ruxolitinib GSE70138 MCF10A Human 3h 0.37uM EID0008
Types Number Response transcription factors
Up-regulation 38 KDM5A; ARID5B; NFAT5; FOXD1; NCOA2; BATF3; NR1D2; POU4F1; BMI1; RBL2; IKZF1; BBX; CIITA; TBX2; IRF4; JUP; FOXF1; HOXB7; ELF1; TCF21; HLTF; TXNIP; HDAC9; ZBTB38; FLNA; PIR; PAX5; BHLHE41; KLF9; MAGED1; LEF1; TLE4; HOXC10; ID4; POU2AF1; MYRF; ZEB2; FOS
Down-regulation 60 TCF12; SMAD4; TBX3; NFIB; CEBPB; ZNF302; ZIC3; DACH1; NEUROD1; ZKSCAN7; RBFOX2; ZNF112; TRIM22; IRF6; ZNF516; GLI2; THAP10; SOX18; MAX; GATAD2A; MXI1; TGFB1I1; CBX6; SUMO1; NR0B1; ZNF532; ZNF304; ZNF232; TCF7L2; BCL6; ZKSCAN1; FOXA1; PRRX1; MBD2; SMARCA1; CITED1; KLF13; CRK; ZEB1; RBPJ; ZBTB18; ZNF22; ZFPM2; SHOX2; NFATC4; ZNF281; NR2F1; ELF5; HOXD1; CRYM; MAFB; SOX11; ST18; HEY1; PBX1; KLF4; CREB1; BASP1; MSX1; CEBPA