Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16837 Ruxolitinib GSE70138 MCF10A Human 3h 1.11uM EID0008
Types Number Response transcription factors
Up-regulation 69 ZMIZ1; DEAF1; NFATC3; BHLHE41; ETV5; SKI; REST; BRD3; NFIB; YWHAB; ZNF302; YEATS4; MEOX1; TBL1XR1; MEIS1; CNOT1; ZNF195; LPIN2; BCLAF1; SOX17; DDX5; MECOM; RBL2; HOXC4; TFDP2; ARNTL; SMARCA2; CBX6; IKZF1; BATF3; FOXC1; PAX8; CITED1; CBFA2T2; CHD9; FOXE1; AFF1; EYA2; ZBED2; PURA; KLF13; KAT6B; CTR9; ZNF217; HLTF; WWTR1; ESR1; FLNA; SMARCA1; NKX2-1; FOSB; CEBPA; SOX9; TCF4; NR2F1; TSC22D1; ID4; ZIC1; LEF1; BASP1; HOXC6; MSX1; TFAP2C; ATF3; ID1; FOS; EMX2; WT1; CRK
Down-regulation 55 NKX3-2; RLF; DPF2; ABT1; MEN1; ETS2; SAFB2; SIAH2; BAZ2B; PLAGL1; KLF2; PAXBP1; TRIM22; TCEB2; TOX3; TCF21; ZNF175; HLX; CREM; LIN28A; FOXN3; ST18; SATB1; MYBL1; TRIM16; MNDA; REL; ZHX2; BCL6; GATA6; NANOG; BCL11A; HMGB3; HMGB2; SAP30; BNC2; KLF5; ELF1; ZBTB20; FOXF1; PITX1; CITED2; HIRA; TWIST1; JUP; LMCD1; DACH1; MYRF; FLI1; MYB; ZNF91; ZEB2; KDM5D; HEY1; MEIS2