Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16836 Ruxolitinib GSE70138 MCF10A Human 3h 3.33uM EID0008
Types Number Response transcription factors
Up-regulation 35 NR3C1; GATA2; TCFL5; TLE4; VDR; FOSL2; EGR3; RCOR1; EGR1; MAGED1; SAP18; TBX2; ZEB2; DACH1; JARID2; JAK2; BMI1; RXRA; MNDA; KLF10; FLI1; KLF2; MYB; WT1; RYBP; TFEC; PBX3; IRF8; ZNF331; GATA6; AEBP1; ID4; CREB1; EGR2; POU2AF1
Down-regulation 36 ZBTB16; CITED1; MBD2; CEBPB; SMARCA1; ZNF532; HOXB13; REPIN1; TFDP2; NKX2-2; RBPMS; ZNF281; PAX6; ZIC1; NFIB; NKX2-1; LITAF; SPDEF; TBX3; SOX2; CRK; TWIST1; FOXA1; ZEB1; TCF7; MECOM; ST18; SATB1; TCF4; ATF3; FOXG1; INSM1; MSX1; KDM5D; CEBPA; PAX8