Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16834 Alpelisib GSE70138 MCF10A Human 3h 0.04uM EID0008
Types Number Response transcription factors
Up-regulation 32 NFE2L1; ZNF131; HMGB1; HMGA1; ATF4; MEIS1; IKZF1; HOXB5; TCF7L1; PAX6; ZFHX4; VPS72; LOXL2; PNRC1; HOXB6; FOSB; ZNF423; BRD4; TWIST1; SMAD1; MXI1; RUNX3; FOXG1; CREB1; SMARCA1; CITED2; MEIS2; BCL11A; ZHX2; SOX11; MYB; FOS
Down-regulation 36 IKBKAP; RNF138; ARID4B; NCOA4; SMAD7; BCL6; TRIM22; HIC2; FOXE1; TSC22D1; SOX9; SATB1; LEF1; NKX3-1; EGR3; HLTF; IRF8; DACH1; ZNF217; FOSL2; TLE1; OSR2; BAZ1A; MAFB; ZFP36L1; MAGED1; ID4; ATF3; MAF; KDM5D; NR4A1; NR2F2; BHLHE41; HOXC10; HOXC6; CEBPA