Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16833 Alpelisib GSE70138 MCF10A Human 3h 0.12uM EID0008
Types Number Response transcription factors
Up-regulation 27 XBP1; HIPK1; NCOA2; TWIST1; PBXIP1; WWP1; ZNF606; C1QBP; TGFB1; HLF; PNRC1; ZNF232; CEBPB; TSC22D2; ZNF512B; ZNF217; PITX2; NANOG; TFAP2C; JUND; ESR1; FOS; ATF3; BHLHE41; PBX1; MSX1; ARNT2
Down-regulation 19 NR2F6; CREB3L1; BASP1; CEBPG; VDR; PAX5; MED1; CUX1; FOXC1; CBX6; CTBP2; SATB1; NR2F1; TSC22D1; TLE1; MEIS1; EMX2; CEBPA; PAX8