Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16832 Alpelisib GSE70138 MCF10A Human 3h 0.37uM EID0008
Types Number Response transcription factors
Up-regulation 58 ZNF274; RSF1; HDAC9; MED13; IFI16; SUB1; HIPK1; AFF1; CNOT6; NCOA2; MYB; BMI1; INSR; IRF1; JARID2; TFDP2; SP140L; BAZ1B; TXNIP; TERF1; TBX2; EGR1; KLF10; IKZF1; UBE2B; ASH2L; BBX; NCOR2; IRF2; TOX3; HOXB7; KAT6B; ELF1; IRF4; MYCL; IRF8; HHEX; IL16; RERE; POU2AF1; TLE1; MLXIP; MAFB; ZSCAN18; ZNF264; FOXF2; CEBPA; ZHX2; BHLHE41; RXRA; HOXB6; CITED2; NR2F2; ID4; LEF1; CREB1; FOS; CRK
Down-regulation 43 TSC22D1; ZNF302; EDF1; RARB; ZNF529; SOX9; TGFB1I1; FOXM1; JUND; SPIB; ZNF281; ZNF22; NPM1; HDGF; LMCD1; BRD2; SIM2; INSM1; CENPF; FOXG1; SMARCA1; ZFHX4; MECP2; ZFP36L1; KLF9; NEUROD1; NR2F1; EMX2; GTF3A; ST18; IRF6; NFIB; EYA1; MEIS1; NKX3-1; HOXD1; NKX2-2; ELF5; TRPS1; HEY1; DACH1; MEIS2; MYRF