Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16831 Alpelisib GSE70138 MCF10A Human 3h 1.11uM EID0008
Types Number Response transcription factors
Up-regulation 23 SSBP2; TSC22D3; SMARCD3; CARHSP1; TBX2; PAX8; SMARCA2; ZNF165; WWC1; TOB1; TSC22D1; KLF9; HOXB7; TXNIP; ID1; MECOM; WT1; PITX1; HOXC10; EMX2; ATF3; FOS; CRK
Down-regulation 31 TP53; MED17; TRIM22; CBFA2T3; NKX2-2; ZNF266; CUX2; KLF10; TOX3; IRF8; CRYM; GATA6; ZNF652; NRIP1; SATB2; EGR3; SOX9; POU2AF1; NR4A1; TWIST1; MAGED1; SATB1; IRX5; TFEC; BASP1; EGR2; MNDA; PAX5; MAFB; MEIS2; CEBPA