Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16830 Alpelisib GSE70138 MCF10A Human 3h 3.33uM EID0008
Types Number Response transcription factors
Up-regulation 28 TSC22D3; NR3C1; RFX5; KDM5D; BTG1; MAZ; MED6; CTBP2; ARID1A; KLF6; MYB; INSR; ID3; FOSB; NR2F2; TLE1; CENPF; PIR; HMGB2; PBX3; HOXD1; WT1; FOS; PAX5; POU2AF1; GATA6; CREB1; CRK
Down-regulation 46 SOHLH2; PAXBP1; ZNF500; ZNF415; ZIC3; DLX5; ZKSCAN7; TRIB3; ZNF529; DDX17; FOXF2; SUB1; ST18; LOXL2; ISL1; RUNX1; ZNF573; NKX2-2; PRRX1; HOXB2; ZNF512B; SATB1; SOX11; ZNF711; TRIM16; DNMT3B; LIN28A; SSX1; DLX2; ELK3; FOXA1; TXNIP; EHF; ELF5; MYT1L; GTF3A; BHLHE40; TRIM29; EGR3; NR2F1; SOX9; LEF1; SMARCA1; EGR2; ZNF586; IKZF1