Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16829 Alpelisib GSE70138 MCF10A Human 3h 10uM EID0008
Types Number Response transcription factors
Up-regulation 69 TSC22D3; NR3C1; ID2; CEBPD; HBP1; SMARCD2; CALCOCO1; TULP3; ELF4; TEAD3; MED13; SUPT4H1; TP63; CITED2; SMAD1; FOXN3; NFATC4; TCF4; NR2F1; IFI16; ID3; TGFB1; HDGF; CEBPB; MXI1; ARID5B; PCGF3; PBX1; VPS72; ZBTB16; TWIST1; TCF7L1; SOX2; ZEB1; PNRC1; BCL6; TRIB3; BTG1; TCF7L2; HOXA5; EHF; ARNT2; TFAP2C; ZNF217; PAX6; CREB1; BNC2; MEIS2; FOXF2; CEBPA; OSR2; ERBB4; ZFPM2; SNAI2; HLX; SHOX2; KLF9; INSR; HEY1; HOXD1; SOX4; SMARCA1; ZIC1; MECOM; TRPS1; TXNIP; BHLHE40; SOX11; ID1
Down-regulation 26 FOSL1; TFDP1; HMGA2; HES1; ETS1; IKBKAP; XBP1; ADRB2; TRIM32; IRF4; CHD7; CRY1; JUN; SIAH2; BATF3; SATB2; EGR1; NRIP1; SATB1; LEF1; EGR3; COPS2; MAGED1; ZEB2; PIR; TOX3