Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16828 Nvp-bez235 GSE70138 MCF10A Human 3h 0.04uM EID0008
Types Number Response transcription factors
Up-regulation 57 GATA2; TSC22D3; FOXO4; XBP1; NR3C1; SMAD3; HIVEP2; NR2F1; FOSB; MEIS1; SMAD2; TBX2; HDAC9; BRCA1; RBPMS; HBP1; SSX1; KAT6B; GTF2IRD1; ZSCAN18; NCOA2; DMTF1; MECOM; KLF6; EYA1; CBX3; SMARCD3; ZFHX3; ELF3; HMGA1; SOX4; ZIC1; PAX8; NR2F2; ZBTB38; NKX3-1; FOXF1; TXNIP; CITED2; JUND; ATF3; MEOX1; BHLHE41; JUP; CREB1; FOXG1; FOS; ZBED2; BASP1; HOXC10; SOX17; POU2AF1; EMX2; KDM5D; ESR1; ID1; CRK
Down-regulation 50 ZNF146; RNF6; SF1; TFCP2; CERS6; CHD1; ZBTB18; CEBPG; GATAD2A; CENPB; WDR77; CHD8; MED17; GATA6; RUNX1; TOX3; DBP; SIAH2; ZNF516; NRIP1; FOXA2; WNT4; PROX1; ZNF573; PIAS4; MNDA; TCEB2; SUB1; TCF7L2; CHD7; TAF1D; TLE4; INSR; NR5A2; HHEX; HLX; IRX5; MYB; BAZ1A; ASCL1; NKX2-1; PITX2; REL; ZNF652; HTATIP2; BCL6; INSM1; SMAD1; ZEB2; CEBPA