Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16826 Nvp-bez235 GSE70138 MCF10A Human 3h 0.37uM EID0008
Types Number Response transcription factors
Up-regulation 79 TSC22D3; MEF2C; TRAK1; SETD2; CREBL2; NR3C1; NR1D2; ZNF589; KDM5B; BRD8; SMARCA2; FOXN3; TXNIP; HR; TBL1XR1; DEK; PPARGC1A; LPIN2; HMGN3; HMGA1; BRD3; SMAD3; NR2F1; HOXB6; PRKDC; HOXC10; ZBTB38; TFDP2; NCOA2; SP100; HOXB7; ATF1; JUP; FOXG1; HMGB2; CITED2; TCF4; KLF5; AFF1; NR1H3; PNRC1; ASH2L; ZNF415; HOXC4; JUND; KLF9; MAF; HBP1; SMARCE1; MECOM; ID3; SOX4; CUX2; TFEC; MEOX1; BASP1; HOXC6; FOXE1; PAX8; DNMT3B; BHLHE41; TRIM22; AHR; NFIB; TRPS1; ID1; ARID5B; KLF6; BHLHE40; CEBPA; ZFPM2; KLF4; FLI1; PBX1; RBPMS; ATF3; NR2F2; EGR3; ID4
Down-regulation 83 ZNF146; FOSL1; IRF3; UBP1; ABT1; ZNF576; ZNF426; MTF1; THAP4; ZNF44; ERF; ZNF551; TAF9; SRF; ZNF562; NUP62; ZNF574; ZNF195; MED17; ZNF263; ZNF430; ZBTB7A; PBX2; MED6; ZNF652; ZNF394; ZNF692; ZNF264; TRIB3; YAP1; ZNF45; ZNF136; ZKSCAN1; ZNF224; RUNX1; SCAND1; TGFB1I1; MED21; ZNF134; ZNF211; CHD7; RNF138; CEBPZ; HLX; ZNF611; PIAS4; CNOT3; MXD1; BCL10; JUN; AEBP1; MNDA; IRX5; ZNF329; IRF7; TOX3; E2F5; REL; MYRF; TRIM16; GATA6; ZNF721; ZNF160; MEIS2; ZBTB18; CRK; TBL1X; BAZ1A; RYBP; SATB1; NKX3-1; HIRA; FOXA1; EGR1; EHF; INSR; ZHX2; BACH2; ZNF91; WT1; INSM1; POU2AF1; IKZF1