Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16825 Nvp-bez235 GSE70138 MCF10A Human 3h 1.11uM EID0008
Types Number Response transcription factors
Up-regulation 44 KDM5A; TSC22D3; NR3C1; CALCOCO1; KLF2; BTG1; HBP1; PRRX2; PPP1R13L; GTF2IRD1; HAND1; CREBL2; DDIT3; BRD3; ATF7IP; GATA3; PNRC1; TULP4; RBBP4; PHF1; HMGB2; NFAT5; PBX3; FOXD1; HMGN3; CITED2; ZBTB38; HMGA1; IRF7; SOX9; SOX4; KLF6; ZNF721; NFE2L3; CRYM; RBPMS; HTATIP2; ZBTB18; TGIF1; FOXO1; BACH2; HOXC10; HOXC6; PAX5
Down-regulation 52 EED; FOSL1; ZSCAN31; ZNF512B; JUN; LZTS1; TAF4; PEG3; ZNF667; MXD1; RNF111; PKNOX2; NLK; ESR1; MEIS1; CBX6; SUB1; ZEB1; ZNF248; FOXF2; ZNF516; DLX5; ZNF239; SOX17; C1QBP; EMX2; CCNE1; PRRX1; NR2F1; TAL1; ST18; PAX6; MSX1; MEOX1; BAZ1A; WWC1; FOXA1; SALL1; TSC22D1; TFEC; CRK; SHOX2; PITX1; ID1; MECOM; EGR2; LEF1; MNDA; PBX1; WT1; PAX8; CEBPA