Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16824 Nvp-bez235 GSE70138 MCF10A Human 3h 3.33uM EID0008
Types Number Response transcription factors
Up-regulation 42 GATA2; TSC22D3; NR3C1; XBP1; NR1D2; DEK; FOXO4; TWIST1; ATF4; BRD8; HBP1; FOXC1; FOXN3; IRF1; PHOX2B; BTG1; KLF2; HMGN3; NCOA4; PHF1; BBX; PTTG1; AGO2; FOXD1; SIM2; PNRC1; CARHSP1; CEBPB; TRIM29; SOX4; TLE4; HMGA1; HIRA; CEBPA; SATB2; CITED2; MXI1; KDM5D; HEY1; HOXC6; CREB1; ID1
Down-regulation 55 NUP62; FOSL1; HES1; TGS1; ZNF273; PTRF; JUN; PGR; ZNF124; ZNF675; NHLH2; ZNF136; KLF1; MED6; ZNF430; ZNF267; AR; NEUROD1; MYRF; TFEC; ZKSCAN1; ZNF667; ZNF394; NFE2L3; FOXO1; ESR1; TCEA2; ELF3; ZBED2; ZNF160; ZNF43; CRK; HIC2; TRIP6; TCF21; ZNF611; NKX2-1; MYT1L; EHF; LITAF; MNDA; TOX3; ZFP36L1; DACH1; ZNF652; MSX1; ZEB2; ZNF512B; EGR2; HOXB6; CRYM; WT1; NR2F2; FOXF1; HOXB2