Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16823 Nvp-bez235 GSE70138 MCF10A Human 3h 10uM EID0008
Types Number Response transcription factors
Up-regulation 54 TSC22D3; HBP1; TRAK1; NR3C1; BTG1; ZMIZ2; ARID5B; FOXO4; MED13; SMAD3; IRF8; CITED2; CREBL2; TRPS1; KLF6; SOX9; UBE2B; MAFB; PAWR; PBXIP1; TXNIP; POU2AF1; ERG; KLF2; CEBPB; TBL1X; IFI16; ZNF544; ZSCAN18; GTF2IRD1; FLI1; CTBP2; ZNF160; HDAC9; MEOX2; BASP1; MYCL; TRIM29; PAX5; ZNF331; CALR; MYB; MAF; CEBPA; KLF4; SATB1; RXRA; TFEC; ZHX2; PBX3; BHLHE41; PBX1; CREB1; CRK
Down-regulation 25 PATZ1; SMARCA5; ETS1; PLAGL2; XBP1; MEIS1; SUB1; DDX17; AR; NFAT5; BHLHE40; MYT1L; STAT4; MSX1; PEG3; MEIS2; THAP11; SMARCA1; BRD4; SNAI2; INSM1; EYA2; HEY1; LEF1; WT1