Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16784 Pf-477736 GSE70138 MCF10A Human 3h 0.37uM EID0008
Types Number Response transcription factors
Up-regulation 49 ZNF274; E2F2; XBP1; TSC22D3; IRF1; KLF2; BCL3; CREB3L2; TBX2; CEBPG; CNOT2; ZSCAN18; EGR1; POU2AF1; ELF1; DDIT3; TBL1X; IKZF1; FOXL2; TRIM16; ZNF217; STAT1; STAT6; SMAD7; NFE2; MYB; LYL1; POU4F1; HLTF; TRIB3; STAT4; BMI1; MYRF; ZBTB38; INSR; ELK3; GATA6; TLE4; CEBPA; NR4A1; SOX4; PIR; JUP; BHLHE40; ID4; PITX1; HOXC6; ATF3; CRK
Down-regulation 50 SOX11; POLR3F; MYT1; ZIC1; CREBL2; ENO1; ZFHX4; NFIB; TSC22D1; TRPS1; ZBED1; MEIS1; UBE3A; ACTL6B; RBPJ; ST18; FOXG1; YBX1; CUX2; ZNF532; INSM1; SUMO1; ZFP36L1; CAMTA1; MEIS2; MAF; MECP2; EYA1; SERTAD2; DACH1; NKX2-2; SOX9; ZNF281; PFDN5; HMBOX1; SALL1; HEY1; NR2F1; COPS2; SMAD1; ZEB1; SOX2; PAX6; NFATC3; AHR; SMARCA1; EGR2; ARNT2; FOS; PAX8