Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16783 Pf-477736 GSE70138 MCF10A Human 3h 1.11uM EID0008
Types Number Response transcription factors
Up-regulation 32 TSC22D3; XBP1; POU4F1; ADRB2; EGR1; ARID5B; SIX1; TBX2; IRF1; TRIB3; HMGB1; NFIL3; STAT1; GTF2IRD1; FOXD1; KLF10; TWIST1; ID3; ZFP36L2; NKX2-1; HOXB7; CEBPA; MYBL1; ZNF281; SMAD1; BHLHE40; CREB1; TXNIP; POU2AF1; ESR1; ID1; ATF3
Down-regulation 52 ZNF426; ELF4; ZBTB16; ZNF93; CENPB; MAF; SHOX2; CUX2; BASP1; NPAS2; RUNX3; ZKSCAN1; MNDA; PAX6; ZNF43; JUN; ZFP36L1; INSM1; ZEB2; FOXE1; PBX3; KDM5D; MEOX1; LIN28A; ZNF665; NEUROD1; NANOG; NKX2-2; CREM; ZNF91; FOSL2; IRF6; MAFB; GATA6; HMGB2; PEG3; NR2F2; CRK; ASCL1; NR4A2; ZIC1; TRPS1; MYRF; PBX1; MYT1L; WT1; MEIS2; SATB1; TOX3; E2F2; ARNT2; IKZF1