Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16782 Pf-477736 GSE70138 MCF10A Human 3h 3.33uM EID0008
Types Number Response transcription factors
Up-regulation 34 NR1H2; NFIL3; TSC22D3; CREB3L2; LITAF; EGR1; TCFL5; XBP1; LIMD1; TCEB2; UBE2I; JUNB; ISL1; PHF1; PIR; CEBPB; NR4A2; ZNF331; KLF2; TRIB3; PTTG1; TBL1X; BTG1; WWTR1; STAT1; BHLHE40; TBX3; TOB1; GATA6; NR4A1; EGR3; ID4; HMGB2; ELF5
Down-regulation 61 ADRB2; NFE2; CNOT6; CTBP1; TFCP2; JUN; GFI1B; ERG; IRF8; ERBB4; TBX21; ZBED1; CRYM; HOXB6; BAZ1B; HIPK2; BASP1; MYCN; TFEB; RERE; HDAC9; ATN1; DACH1; ZNF544; BRD4; IRF6; POLR2A; LYL1; PAX6; TFEC; HLF; CUX2; TRIM22; HOXB2; HIC2; SMAD1; ZKSCAN1; ZNF423; ZFPM2; MNDA; ASCL1; TOX; BNC2; ESR1; TRIP6; ZEB1; MYB; WWC1; JAK2; MYRF; CRK; KLF10; MEF2C; EMX2; NFATC3; SOX9; TOX3; GATA3; E2F2; CEBPA; PAX8