Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16781 Pf-477736 GSE70138 MCF10A Human 3h 10uM EID0008
Types Number Response transcription factors
Up-regulation 61 TSC22D3; KDM5A; RELB; NFIL3; PHF20; FOSB; WWTR1; SOHLH2; BCL3; MNT; MSC; RELA; RNF4; NFKBIA; RFX5; MXD4; SKI; EGR1; RUNX3; TRIM24; PLAGL1; FOXA1; PNRC1; NAB1; AGO2; HOXA5; BATF3; ETS2; NRBF2; SMARCD3; ZBTB1; MITF; FOXF1; RBL2; NR2F1; TCF21; ZBTB38; TOB1; BAZ1A; CREM; HMGB3; CEBPA; FOS; MYB; MYCL; TOX3; PITX2; EHF; MEIS1; PEG3; NR4A1; DACH1; TBX3; PITX1; TWIST1; TCF4; SMARCA1; MAF; GATA6; EGR2; CRK
Down-regulation 62 MYC; ADRB2; HMGA2; RFX7; TAF1A; GTF2I; VGLL4; SIX3; GABPA; GCFC2; ZNF273; MLX; SP140L; ETS1; TAF9B; MED1; GTF3A; APEX1; BRIP1; MYT1L; HMGB1; ZMYND8; SP2; PRRX1; ZNF117; HEY2; SMARCC2; ZNF43; CHD9; CERS4; SOX13; MDM2; TRIM22; SALL2; NRIP1; ID3; CITED2; HIPK3; HMGA1; KAT2B; ZNF91; DLX5; HHEX; STAT1; SOX9; SAP30; ZBED2; FLI1; ST18; SATB1; SOX4; SMAD1; BACH2; HMGB2; AEBP1; ZIC1; ZHX2; PAX5; CREB1; LEF1; POU2AF1; PAX8